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Tacrine (tetrahydroaminoacridine; THA) and Lecithin in Senile Dememtia of the Alzheimer Type:A Multicentre Trial
BMJ 300:495-499, Chatellier,G.,et al, 1990
See this aricle in Pubmed

Article Abstract
Neither short term nor long term treatment with oral tacrine at dosages lower than 125 mg/day improves the symptoms of Alzheimer's disease. Moreover,these dosages may induce hepatitis(nine of 67 patients in this series).
 
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adverse drug reaction
Alzheimer's disease
Alzheimer's disease,treatment of
anticholinesterase
dementia
hepatitis
lecithin
liver disease
tetrahydroaminoacridine
treatment of neurologic disorder

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