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Ischemic Stroke Due to Protein C Deficiency
Stroke 21:1077-1080, Kohler,J.,et al, 1990
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Article Abstract
Plasma protein C exerts anticoagulatory effects by inactivating factors V and VIII.Hereditary protein C deficiency is transmitted as an autosomal dominant disorder.Homozygous individuals usually develop purpura fulminans as newborns;heterozygous protein C-deficient individuals are at increased risk for venous thrombosis and pulmonary embolism.However,arterial thrombosis has been only rarely observed.We describe a young patient with heterozygous protein C deficiency who experienced a severe stroke due to thrombotic occlusion of the left middle cerebral artery.
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CAT scan,abnormal
cerebrovascular accident
cerebrovascular accident,young adult
middle cerebral artery,occlusion of
protein C deficiency
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