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We describe a 42-year-old woman who developed superior sagittal and left transverse sinus thrombosis associated with prolonged e-aminocaproic acid therapy for menorrhagia.This antifibrinolytic agent has been used in women with menorrhagia to promote clotting and reduce blood loss.Although increased risk of thromboembolic disease has been reported during treatment with e-aminocaproic acid,cerebral sinus thrombosis has not been previously described.Careful use of e-aminocaproic acid therapy is recommended. |
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