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Cerebral Venous Thrombosis in Systemic Lupus Erythematosus
Stroke 21:1226-1231, Vidailhet,M.,et al, 1990
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Article Abstract
We describe six cases of cerebral venous thrombosis in patients with systemic lupus erythematosus.In one patient,cerebral venous thrombosis was the initial manifestation of lupus;in the five others,it occurred 1-33 years after the diagnosis of lupus.The main clinical features of cerebral venous thrombosis were persistent headache in all six patients,focal symptoms in four,and seizures in three;papilledema was present in only one patient.Cerebral venous thrombosis was diagnosed based on angiography or magnetic resonance imaging.Both the transverse(in five patients)and the superior sagittal(in three)sinuses were involved.Extracranial arterial and/or venous thrombosis were present in three patients,abortion in two, thrombocytopenia in four,and lupus anticoagulant in three.The neurologic symptoms resolved rapidly in five patients treated with steroids and heparin.Cerebral venous thrombosis should be suspected in patients with lupus who complain of persistent headache,especially in the presence of neurologic symptoms.
 
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abortion,spontaneous
cerebral venous thrombosis
headache
lupus anticoagulant
MRI
MRI,abnormal
neurologic symptoms
papilledema
seizure
superior sagittal sinus thrombosis
systemic lupus erythematosus
systemic lupus erythematosus,neurologic complications with
thrombocytopenia
treatment of neurologic disorder

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