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Ganciclovir in the Treatment of Progressive AIDS-Related Polyradiculopathy
Neurol 40:569-574, Miller,R.G.,et al, 1990
See this aricle in Pubmed

Article Abstract
We present 7 HIV-infected patients with a unique,subacute,progressive polyradiculopathy.All had AIDS,sacral sensory loss,acute urinary retention,and progression to flaccid paraparesis in days to weeks. Cytomegalovirus was cultured from spinal fluid of 4 patients,and postmortem examination on the 1st 5 patients disclosed an inflammatory polyradiculopathy with cytomegalic inclusions.The inclusion-bearing cells were immunocytochemically positive for cytomegalovirus.Two patients who received early anti-cytomegalovirus treatment with ganciclovir improved. Thus,early recognition and treatment with ganciclovir may be effective in this otherwise fatal condition.
 
Related Tags
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acquired immunodeficiency syndrome
antiviral agents
cerebrospinal fluid,abnormal
cerebrospinal fluid,culture of
cerebrospinal fluid,culture of,viral
cerebrospinal fluid,elevated protein of
cytomegalovirus infection
ganciclovir
Guillain Barre syndrome
hypoglycorrhachia
neuropathology
pleocytosis of cerebrospinal fluid
polyradiculoneuropathy
treatment of neurologic disorder

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