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CIDP of Childhood:Treatment with High-Dose Intravenous Immunoglobulin Neurol 41:828-830, Vedanarayanan,V.V.,et al, 1991 See this aricle in Pubmed Article Abstract We treated four children with chronic inflammatory demyelinating polyradiculoneuropathy(CIDP)with high-dose intravenous immunoglobulin (IVIG).All patients received 400 mg/kg of IVIG a day for 5 days during relapses,and one patient received additional periodic infusions of 400 mg/ kg.All patients showed excellent recovery of motor strength following each relapse that was treated with IVIG.Compared with plasmapheresis(which was used to treat relapses earlier),recovery of each relapse that was treated with IVIG.Compared with plasmapheresis.There were no side effects with IVIG treatments as compared with plasmapheresis with which two children had infection of central lines with Staphylococcus epidermidis,one had profuse bleeding from accidental extrusion of a central line,and one had multiple episodes of major venous thromboses.High-dose IVIG was a safe and effective adjunctive therapy for childhood CIDP in these four patients.

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(click to filter results - removes previous filter) children gammaglobulin therapy,intravenous neuropathy,peripheral,treatment plasmapheresis polyneuropathy polyneuropathy,chronic inflammatory demyelinating polyneuropathy,chronic inflammatory demyelinating,childhood treatment of neurologic disorder

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