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Brain Biopsy in the Management of Focal Encephalitis
JNNP 54:1001-1003, Anderson,N.E.,et al, 1991
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Article Abstract
The value of a brain biopsy in diagnosis and management of suspected herpes simplex encephalitis was studied in 29 patients(16 prospectively and 13 retrospectively).The biopsy showed herpes simplex encephalitis in eight,culture-negative encephalitis in 14,and was normal in three patients.It provided an alternative diagnosis in four patients,for two of whom curative treatment was available.The biopsy was complicated by a fatal intracranial haemorrhage in one patient.The low yield of alternative diagnoses suggests that a brain biopsy is not justified in the routine investigation of focal encephalitis.
 
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brain biopsy
brain biopsy,complications of
brain biopsy,indication
encephalitis
encephalitis,focal
herpes simplex encephalitis
herpes simplex encephalitis,diagnosis of
herpes simplex encephalitis,differential diagnosis of
intracerebral hemorrhage
mortality

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