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Temporal Lobectomy for Intractable Epilepsy in Patients Over Age 45 Years Neurol 42:662-665, McLachlan,R.S.,et al, 1992 See this aricle in Pubmed Article Abstract Surgical management of uncontrolled focal epilepsy is most commonly carried out in young adults with good results,but there has been some doubt about the effectiveness of cortical resection in older individuals. We assessed the outcome of temporal lobectomy done after age 45 years in 20 patients with intractable epilepsy followed for more than 2 years after surgery.During a mean follow-up of 5 years,six patients(30%)were seizure- free and 44%with>90%seizure reduction in 68 younger patients aged 17 to 45 years;the differences do not achieve statistical significance.The outcome was better for complex partial seizures than for secondarily generalized seizures.Complications were not greater than in the younger patients.The findings indicate that surgery is an effective treatment alternative for intractable temporal lobe epilepsy in older patients since two of three of these patients will obtain satisfactory seizure control.

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(click to filter results - removes previous filter) seizure seizure,intractable seizure,intractable,treatment of seizure,prognosis in adults seizure,surgical treatment of seizure,treatment of temporal lobectomy

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