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Overall,multiple-infarct index cases had more cerebral infarcts,more cortical and subcortical left hemisphere infarcts,higher mean ventricular volume to brain volume ratio,more extensive enlargement of the body of the lateral ventricles and cortical sulci,and a higher prevalence of white matter lucencies.Among multi-infarct cases and control subjects the most frequent site of infarction was the subcortical region,and the most frequent pattern of infarction was lacunar.Stepwise logistic regression analysis examined cranial computed tomography as well as other factors and showed that level of education,stroke severity,left cortical infarction, and diffuse enlargement of the left lateral ventricle were the best overall predictors of multi-infarct dementia.Conclusions:Level of education,stroke severity,and left hemisphere infarction may be predictors of multi-infarct dementia. |
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