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Ventriculo-pleural Shunting for Adult Hydrocephalus
Br J Neurosurg 2:503-505, Megison,D.P.&Benzel,E.C., 1988
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Article Abstract
X-linked hydrocephalus is the most common form of inherited hydrocephalus, and is associated with severe neurological deficits and premature death.We have shown that mutations in the gene encoding L1 neural cell adhesion molecule result in X-linked hydrocephalus,which enables improved prenatal diagnosis and investigation of the role of this molecule in sporadic cases.Here we report two pedigrees with apparently sporadic hydrocephalus in which we demonstrated a disabling mutation in the L1 gene.This enabled us to provide definitive prenatal diagnosis at ten weeks gestation.
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hydrocephalus
hydrocephalus,treatment of
iatrogenic neurologic disorders
neoplasm,intracranial with metastasis extracranially
pleural effusion
pneumothorax
shunt procedure,ventricular
shunt procedure,ventricular-complications of
shunt procedure,ventriculo-pleural
treatment of neurologic disorder
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