|
|
|
|
Eosinophilia-myalgia syndrome(EMS)is a newly described syndrome associated with use of L-tryptophan.A neuropathy with features of axonal degeneration has also been described in conjunction with EMS.Demyelinating polyneuropathy is not a well recognised association of the syndrome.The two patients with EMS reported presented with profound weakness and sensory loss and were found to have clinical,electrophysiological and pathological evidence of a chronic demyelinating polyneuropathy.The concurrence of this neuropathy with EMS,as well as several other features of their illness,is suggestive of an immune mediated mechanism in the pathophysiology of EMS. |
|