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Intranasal Apomorphine in Parkinsonian On-Off Fluctuations
Arch Neurol 49:482-484, vanLaar,T.,et al, 1992
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Article Abstract
The efficacy of intranasal apomorphine was assessed in seven patients with Parkinson's disease and severe levodopa(L-dopa)-related"off-period" disabilities.All patients responded favorably to treatment with intranasal apomorphine.The speed and the quality of motor response and the pharmacokinetic profile showed results similar to those seen after subcutaneous injection of apomorphine administered by insulin pen syringe. The simplicity in the technique of intranasal apomorphine administration was found to be superior by all patients.
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apomorphine
intranasal medication
Parkinson disease
Parkinson disease,on-off phenomena in
Parkinson disease,treatment of
treatment of neurologic disorder
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