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Four major factors were found:cognitive impairment,cerebrovascular disease,disturbed behavior,and depressive symptoms.The comparison of these factors with the clinical diagnoses showed that(1)the cognitive impairment factor discriminated demented cases from nondemented;(2)the cerebrovascular disease factor discriminated vascular dementia from AD cases and nondemented;(3)the disturbed behavior factor discriminated AD cases from vascular dementia cases and nondemented,indicating behavioral changes characteristic of AD.This finding,if replicated,would have implications for the construction of diagnostic criteria for AD. |
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