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Pneumocystis Carinii Pneumonia During Steroid Taper in Patients with Primary Brain Tumors Am J Med 94:216-219, Slivka,A.,et al, 1993 See this aricle in Pubmed Article Abstract Pneumocystis carinii causes life-threatening pneumonitis(PCP)_in immunocompromised individuals.In the non-AIDS(acquired immunodeficiency syndrome)population,PCP is frequently associated with corticosteroid therapy,and the rodent model uses cortocosteroid-induced immunosuppression to provoke PCP.Although patients with intracranial tumors are frequently treated with long courses of corticosteroids,there have been very few descriptions of PCP in this population.We report the diagnosis and treatment of PCP in four patients over a 12-month period with intracranial neoplasms who developed symptoms during corticosteroid taper.Effective prophylaxis against PCP exists and should be considered for patients with intracranial neoplasms receiving long-term steroids.

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(click to filter results - removes previous filter) neoplasm,intracranial neoplasm,primary intracerebral neoplasm,primary of CNS opportunistic infection pneumocystis carinii steroid steroid therapy,CNS treatment and complications with treatment of neurologic disorder

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