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Symptoms,signs,chest radiographic appearance,cerebrospinal fluid cell counts and chemistries,and mortality were similar in both groups(p=NS). Medial CD4+cell counts were lower in HIV-infected patients(median 99/mm3, range 7 to 251,versus 384/mm3,range 171 to 724 in those without HIV infection,p=0.007).Intracerebral mass lesions were more common in the HIV- infected group(60%versus 14%in the uninfected group,p=0.01),although the presence of a mass did not correlate with focal neurologic deficits, altered level of consciousness,or mortality.With the exception of an increased incidence of intracerebral mass lesions in HIV-infected individuals,HIV infection appears to have little impact on the findings and in-hospital mortality of tuberculous meningitis. |
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