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Cerebral dynamic computed tomography and cerebral angiography were used to measure cerebral circulation in the first case,that of a 20-year-old woman with MELAS.The second subject was a 13-year-old female who was studied with xenon-enhanced computed tomography.The cerebral blood flow studies were performed 3-72 hours after the onset of strokelike episodes.Serial cerebral angiography,dynamic computed tomography,and xenon-enhanced computed tomography showed vasodilation localized in the affected cerebral cortexes during strokelike episodes,without any reduction in regional cerebral blood flow.Our study suggests that the strokelike episodes associated with MELAS are different in origin from ischemic stroke. |
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