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MRI evidence of apparent ongoing disease activity was seen more frequently in patients believed to have ctive multiple sclerosis in the preceding year(13 of 21)than in patients who had been in clinical remission for at least the 2 preceding years(2 of 8).Although clinical evidence of new disease activity was much less common in patients with active,chronic- progressive disease(1 of 8)than in patients with active,relapsing disease (9 of 13),the proportion of patients with either infrequent relapses, frequent relapses,or slow chronic-progressive disease in the preceding year in whom MRI activity developed and the pattern of this new MRI activity was similar between these types of active patients.This finding suggests that although there are differences in the clinical expression of disease,there may not be a fundamental difference between mild,active relapsing and mild,active progressive multiple sclerosis as defined by MRI. |
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gadolinium MRI MRI,abnormal MRI,contrast enhanced MRI,demyelinating disease MRI,serial MRI,spinal cord multiple sclerosis
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