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Transient Ischemic Attacks in Younger and Older Patients:A Comparative Study of 798 Patients in South Africa
Stroke 24:947-953, Giovannoni,G.&Fritz,V.U., 1993
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Article Abstract
In younger patients the presenting transient ischemic attack occurred less frequently in the vertebrobasilar territory(9%versus 21%,P=.03).Risk factor analysis revealed significant differences between the groups,with hypertension,previous smoking history,ischemic heart disease,and peripheral vascular disease being more common in the older group.Migraine and valvular heart disease were more common in the younger group. Approximately 60%of the patients in each group had multiple etiologies.The most common etiology was atheromatous cerebrovascular disease in both groups((74%versus 37%[P<.0001]in the older and younger groups, respectively).Other significant etiologic differences included fibromuscular dysplasia,mitral valve prolapse,and use of oral contraceptives occurring more frequently in the younger group,and ischemic heart disease occurring more frequently in the older group.This study reveals the clinical and etiologic differences between younger and older patients with transient ischemic attack.The importance of multiple etiologies in both groups of patients has diagnostic and management implications.
 
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cerebrovascular accident
cerebrovascular accident,young adult
cerebrovascular disease,risk factors in
migraine
mitral valve lesion
old age,neurology of
risk factors
transient ischemic attack
transient ischemic attack,etiology of
transient ischemic attack,young adult

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