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Systemic Histiocytosis Presenting as Multiple Sclerosis Ann Neurol 33:549-554, Smith,M.E.,et al, 1993 See this aricle in Pubmed Article Abstract A patient resembling one with progressive multiple sclerosis in clinical presentation and by magnetic resonance imaging was studied in detail.Some features atypical for multiple sclerosis prompted a persistent search for an alternative cause.The diagnosis of a non-Langerhans systemic histiocytosis involving brain and bone was established and showed a partial response to radiation therapy.This patient illustrates the continued importance of a broad approach to the evaluation of possible multiple sclerosis,with particular attention to atypical features.

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(click to filter results - removes previous filter) bone scanning Erdheim-Chester disease misdiagnosis MRI MRI,abnormal multiple sclerosis multiple sclerosis,misdiagnosis

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