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Myasthenic Crisis Response to Plasmapheresis Following Failure of Intravenous Gammaglobulin
Arch Neurol 50:837-840, Stricker,R.B.,et al, 1993
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Article Abstract
Myasthenic crisis is a potentially life-threatening complication of myasthenia gravis that required aggressive therapy.We describe four patients in whom myasthenic crisis developed and who failed to respond to initial treatment with intravenous y-globulin.All four patients subsequently responded to intensive plasma exchange.Based on our experience,plasmapheresis appears to be superior to intravenous y-globulin for the treatment of myasthenic crisis in certain patients.Prognostic factors that determine the effectiveness of intravenous y-globulin vs plasmapheresis in these patients merit further investigation.
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emergencies,neurologic
gammaglobulin therapy,intravenous
myasthenia gravis,treatment of
myasthenic crisis
plasmapheresis
treatment of neurologic disorder
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