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Thirty-nine patients(10%)had 41 stroke events(23 ischemic,18 hemorrhagic); 22 of these patients(56%)died from stroke.The cumulative ischemic stroke risk was 5%at 5 years and 12%at 15 years.Prior myocardial infarction was the only independent predictor(relative risk[RR],3.1;P<.05).The cumulative hemorrhagic stroke risk was 3%at 5 years and 17%at 15 years.Systolic hypertension(RR,4.8;P<.01)and insulin-dependent diabetes(RR,2.2;P<.005), and prior myocardial infarction(RR,1.8;P<.01).Patients with chronic lower limb ischemia,notably those with prior myocardial infarction,are at high risk for ischemic stroke.Those with systolic hypertension or insulin- dependent diabetes mellitus are at high risk for hemorrhagic stroke. |
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