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MRI Pallidal Hyperintensity & Brain Atrophy in Cirrhotic Pts:2 Different MRI Patterns of Clin Deterior?
Neurol 43:2570-2573, Kulisevsky,J.,et al, 1993
See this aricle in Pubmed
Article Abstract
In cirrhotic patients,even in a stable nonencephalopathic state,MRI may show cerebral atrophy and increased signal in globus pallidus on T1- weighted sequences.We investigated the relationship between cerebral atrophy and increased pallidal signal and the clinical status of 30 cirrhotic patients.We found a weak association between the two MRI findings.There were different patterns of clinical variables related to the imaging findings.Performance on motor tasks involving speed correlated with the pallidal signal and plasma ammonia levels but not with atrophy. Test results for memory and frontal-premotor function were associated with brain atrophy but not with the pallidal signal or with ammonia.
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ammonia
basal ganglia
cerebral cortical atrophy
cirrhosis
globus pallidus
globus pallidus,lesion of
globus pallidus,lesion of,bilateral
liver disease
MRI
MRI,abnormal
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