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In the classical corneomandibular reflex(CMR),corneal stimulation elicits a bilateral eyelid blink and a brisk anterolateral jaw movement.We here describe 14 patients with a spontaneous palpebromandibular(eyelid-jaw) synkinesia(SPMS)in whom jaw movements,similar to those in CMR,regularly accompanied spontaneous eye blinks without an external corneal stimulus.We conclude that SPMS is pathophysiologically the same as the eyelid-jaw synkinesia of CMR and both synkinesias originate centrally,probably in the pons.In CMR,the jaw movement is primarily related to the blink rather than the corneal stimulus,but corneal stimulation may be necessary to overcome a higher threshold for expression of the synkinesia than in patients with SPMS.Like CMR,SPMS emerges in patients with upper brainstem or bilateral cerebral lesions and SPMS may therefore be a useful localizing clinical sign. |
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blinking brainstem,infarction of brainstem,lesion of cerebrovascular accident multiple sclerosis neurologic signs palpebromandibular synkinesia pathologic reflex pons,infarction of
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