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Cerebral Microembolism in Symptomatic and Asymptomatic High-Grade Internal Carotid Artery Stenosis Neurol 44:615-618, Siebler,M.,et al, 1994 See this aricle in Pubmed Article Abstract Using transcranial Doppler(TCD)ultrasonography in patients with high-grade (>/=70%)internal carotid artery(ICA)stenosis,we examined the relation between the rate of TCD-detected silent microembolism of the ipsilateral middle cerebral artery and a history of recent(<121 days)ischemic symptoms attributable to the diseased ICA.In the so-defined neurologically symptomatic group(n=33 patients),silent microembolic events occurred in 27 subjects(overall mean rate,14/h=/-29).Among 56 neurologically asymptomatic patients matched for the degree of ICA stenosis,only nine showed such events(overall mean rate,0.35/h=/-1.4).Across all 89 patients studied,an individual microembolic event rate>/=2/h had a positive predictive value of 0.88 for a history of recent symptoms.Our data suggest that TCD monitoring can provide reliable paraclinical evidence of"unstable ICA disease".

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(click to filter results - removes previous filter) carotid artery disease carotid artery disease,asymptomatic carotid artery stenosis cerebral embolism doppler doppler,transcranial embolism,silent microemboli

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