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Ten Year Cerebrovascular Morbidity and Mortality in 68 Year Old Men with Asymptomatic Carotid Stenosis BMJ 310:294-298, Ogren,M.,et al, 1995 See this aricle in Pubmed Article Abstract Fifty men had a stroke,six of these were haemorrhagic.Another 11 had a transient ischaemic attack.Eighteen of the men with carotid stenosis(21.6 events/1000 person years)and 43 of the men with normal carotid arteries (14.8 events/1000 person years)had a stroke or transient ischaemic attack (P=0.188).Men with atrial fibrillation had an increased rate of cerebrovascular events(36.7/1000 person years(P=0.048).The highest rate was found in men with asymptomatic disease of the leg arteries 38.6/1000 person years(P<0.001).The increased risk of stroke or transient ischaemic attack in this group remained after multivariate analysis(relative risk 2. 0;95%confidence interval 1.1 to 3.7).In this cohort carotid stenosis was not associated with an increased risk of stroke.Part of this lack of association was explained by the high mortality from ischaemic heart disease in men with severe stenosis.Twenty seven of the 61 cerebrovascular events,however,occurred in men who had normal carotid arteries,normal ankle pressure,and no atrial fibrillation.

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(click to filter results - removes previous filter) atherosclerosis,generalized carotid artery disease carotid artery disease,asymptomatic carotid artery disease,natural history of carotid artery stenosis cerebrovascular accident cerebrovascular disease cerebrovascular disease,risk factors in mortality peripheral vascular disease prognosis risk factors

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