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Vitamin C and Risk of Death from Stroke and Coronary Heart Disease in Cohort of Elderly People
BMJ 310:1563-1566, 15481995., Gale,G.R.,et al, 1995
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Article Abstract
Mortality from stroke was highest in those with the lowest vitamin C status.Those in the highest third of the distribution of vitamin C intake had a relative risk of 0.5(95%confidence interval 0.3 to 0.8)compared with those in the lowest third,after adjustment for age,sex,and established cardiovascular risk factors.The relation between vitamin C intake and stroke was independent of social class and other dietary variables.A similar gradient in risk was present for plasma ascorbic acid concentrations.No association was found between vitamin C status and risk of death from coronary heart disease.In elderly people vitamin C concentration,whether measured by dietary intake or plasma concentration of ascorbic acid,is strongly related to subsequent risk of death from stroke but not from coronary heart disease.
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antioxidant
ascorbic acid
atherosclerosis,generalized
cerebrovascular accident
cerebrovascular accident,prevention of
cerebrovascular disease,risk factors in
cholesterol,LDL
diet
fibrinogen
free radical
mortality
prevention of neurologic disorders
risk factors
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