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Prevalence and Outcome of Symptomatic Carotid Lesions in Young Adults
BMJ 310:1363-1366, Carolei,A.,et al, 1995
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Article Abstract
Carotid stenoses of 50-99%and occlusions were found in 38 patients(15.8%). Both conditions were significantly more frequent in patients aged over 35 and in those with hpertension,diabetes mellitus,and stroke at entry.The standardised mortality ratio at five years was 10.5(95%confidence interval 5.0 to 19.3).Survival of patients with stenoses of 0.49%and occlusions was significantly better than that of patients with stenoses of 50-99%.Carotid stenosis of 50-99%was an independent predictor of death(hazard ratio 7.9; 95%confidence interval 2.2 to 29)and non-fatal stroke(hazard ratio 7.4;1.5 to 37.4).The prevalence of carotid stenosis or occlusion in young adults after a cerebrovascular event is low.Though patients with high grade symptomatic carotid stenosis are at risk of non-fatal and fatal events, patients with internal artery occlusion apparently have a benign prognosis.
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cerebrovascular accident,young adult
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