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A Comparison of Magnesium Sulfate with Phenytoin for the Prevention of Eclampsia NEJM 333:201-205, 2501995., Lucas,M.J.,et al, 1995 See this aricle in Pubmed Article Abstract Ten of 1089 women randomly assigned to the phenytoin regimen had eclamptic convulsions,as compared with none of 1049 women randomly assigned to magnesium sulfate(P=0.004).There were no significant differences in any risk factors for eclampsia between the two study groups.Maternal and infant outcomes were also similar in the two study groups.Magnesium sulfate is superior to phenytoin for the prevention of eclampsia in hypertensive pregnant women.These results validate the long-practiced use of magnesium sulfate in the prevention of eclampsia.

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(click to filter results - removes previous filter) anticonvulsants dilantin eclampsia hypertension magnesium sulfate pre-eclampsia pregnancy,neurologic complications in prevention of neurologic disorders seizure seizure,peripartum seizure,pregnancy

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