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Cardiac Involvement in a Large Kindred with Myotonic Dystrophy:Quant Assess & Relation to Size of CTG Repeat Expansion
JAMA 274:813-819, Tokgozoglu,L.S.,et al, 1995
See this aricle in Pubmed

Article Abstract
Compared with age-matched normals,patients with myotonic dystrophy(n=25) were more likely to have conduction abnormality(52%vs 9%),mitral valve prolapse(32%vs 9%),and wall motion abnormality(28%vs 0%)(all P<.05).Left ventricular ejection fraction and stroke volume were reduced compared with normals matched for age and heart rate(P<.05),whereas Doppler indexes of diastolic function were only marginally altered.Using multivariate analysis,the number of CTG repeats(range,69 to 1367;normal,
 
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atrioventricular block
echocardiogram
electrocardiogram,abnormal
genetic testing
heart block
mitral valve prolapse
muscular dystrophy
muscular dystrophy,cardiovascular changes with
myotonia dystrophica
trinucleotide repeats

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