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Rising Primary Malignant Brain Tumor Mortality in the Elderly:A Manifestation of Differential Survival Arch Neurol 52:571-575, Rigg,J.E., 1995 See this aricle in Pubmed Article Abstract Increasing primary malignant brain tumor mortality rates among the oldest age groups in the United States from 1962 to 1989 were directly proportional to the increasing population size of these age groups. Comparisons between age-specific mortality rates are generally considered valid since they are inherently age-and sex-matched.Moreover,age-specific mortality rates should not be related to population size.Rather than implying improved diagnosis or enhanced carcinogenesis,these results suggest that differential survival and its effect on the surviving gene pool in an aging population is an alternative explanation for the observed increase in primary malignant brain tumor mortality among the elderly.

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