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Surgical Treatment of Temporal Lobe Epilepsy:Clinical, Radiological and Histopathological Findings in 178 Patients
JNNP 58:666-673, Zentner,J.,et al, 1995
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Article Abstract
Overall,structural abnormalities were detected by MRI in 82.7%of all patients.The mean postoperative follow up period was three years.The data show that the presence of focal lesions or Ammon's horn sclerosis as determined by histopathological examination is associated with improved postoperative seizure control compared with patients without specific pathological findings.Brain MRI was very sensitive in detecting neoplasms; however,its sensitivity and specificity were limited with respect to non- neoplastic focal lesions and Ammon's horn sclerosis.Improvement of imaging techniques may provide a more precise definition of structural lesions in these cases and facilitate limited surgical resections of the epileptogenic area rather than standardised anatomical resections.
 
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