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Fifty-one studies fulfilled our criteria.Overall mortality was 1.62%(95% confidence 5 interval[CI],1.3 to 1.9),and the risk of stroke and/or death was 5.64%(95%CI,4.4 to 6.9).However,there was significant heterogeneity of risk of stroke and/or death(P<.001).The risk varied systematically with the methods and the authorship of the study.The risk of stroke and/or death was highest in studies in which patients were assessed by a neurologist after surgery(7.7%;95%CI,5.0 to 10.2)and lowest in studies with a single author affiliated with a department of surgery(2.3%;95%CI,1. 8 to 7.2).After correcting for study methodology,there was no temporal trend in the risk of stroke and/or death between 1980 and 1995.The reported risks of endarterectomy for symptomatic carotid stenosis show significantly greater variability than would be expected by chance. However,much of this variability can be accounted for by differences in methodology and authorship.The 5.6%overall risk of stroke and/or death is consistent with present guidelines. |
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carotid artery disease carotid artery stenosis carotid artery stenosis,symptomatic cerebrovascular accident cerebrovascular accident,postoperative endarterectomy,carotid endarterectomy,carotid-complications of endarterectomy,carotid-morbidity and mortality with mortality review article risk factors
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