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Twenty-five studies fulfilled our criteria.Mortality within 30 days of endarterectomy was 1.31%for asymptomatic stenosis and 1.81%for symptomatic stenosis(odds ratio[OR],0.69;95%confidence interval[CI],0.49 to 0.99).The risks of fatal stroke were 0.47%and 0.91%,respectively(OR,0.57;95%CI,0.34 to 0.98).The overall risk of stroke and/or death was 3.35%for asymptomatic and 5.18%for symptomatic stenosis(OR,0.61;95%CI,0.51 to 0.74).Mortality and the risk of stroke and/or death due to carotid endarterectomy are significantly lower for asymptomatic than symptomatic stenosis.These findings are consistent across virtually all studies and are likely to be widely generalizable. |
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