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Human herpesvirus-6(HHV-6)is implicated in a variety of neurologic diseases.We report a previously healthy elderly women with progressive spastic paraparesis.At autopsy the spinal cord showed widespread demyelination,axonal loss,and chronic inflammation.HHV-6 DNA was amplified,using polymerase chain reaction,from spinal cord tissue,and glial cells were immunoreactive with an HHV-6 antibody.These findings suggest that HHV-6 may cause myelopathy. |
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