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Progressive Deterioration of Intellect and Motor Function Occurring Several Decades after Cranial Irradiation ARch Neurol 53:814-818, Duffey,P.,et al, 1996 See this aricle in Pubmed Article Abstract Latent intervals approaching 2 decades have been reported in cases of radiation necrosis following cranial irradiation,but a similar or greater delay before the onset of radiation encephalopathy has not been described previously.This report indicates that a diagnosis of radiation encephalopathy much be considered when any individual who has received cranial irradiation presents with deterioration in intellectual or motor functions,whatever the interval.

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