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Subacute Leukoencephalitis Caused by CNS Infection with Human Herpesvirus-6 Manifesting as Acute Multiple Sclerosis
Neurol 47:145-148, Carrigan,D.R.,et al, 1996
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Article Abstract
Several recent reports have documented the neuroinvasiveness of human herpes virus-6(HHV-6)in infants with primary HHV-6 infections,in children and adults with AIDS,in recipients of bone marrow transplants,and in immunologically intact adults and children.CNS infections with HHV-6 can be subacute and are frequently associated with diffuse or multifocal demyelination.We analyzed the CNS tissues of a young woman who died of a demyelinative disease,which was clinically and histopathologically diagnosed as acute multiple sclerosis,for active HHV-6 infection by immunohistochemical staining.The tissues contained a dense and disseminated active HHV-6 infection that was intimately related to the pathologic changes present.
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central nervous system,infection of
herpes virus
herpes virus infection
human herpesvirus 6
leukoencephalitis
misdiagnosis
multiple sclerosis
multiple sclerosis,acute
multiple sclerosis,differential diagnosis of
multiple sclerosis,misdiagnosis
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