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Pituitary Enlargement on Magnetic Resonance Imaging in Congenital Hypothyroidism
Arch Pediatr Adolesc Med 150:623-628, Desai,M.P.,et al, 1996
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Article Abstract
Magnetic resonance imaging showed homogenous diffuse enlargement of the pituitary gland in all patients.The superior margin of the gland was flat in five patients and convex in the rest with suprasellar extension and partial or complete obliteration of the infundibulum in three and mild compression of optic chiasm in two,thus mimicking a sellor or suprasellar tumor.Pretreatment pituitary mean vertical height in the coronal plane was 10.02 plus or minus 2.24 mm with a post-treatment regression to 4/92 plus or minute 1.11 mm(P<.001,Student's t test)and restoration of clinical and hormonal euthyroid status.Awareness of pituitary enlargement and the rare occurrence of neurologic symptoms and chiasmal syndrome are important in children with longstanding congenital hypothyroidism.
 
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chiasmal syndromes
hypothyroidism
hypothyroidism,congenital
MRI
MRI,abnormal
neuroendocrinology
optic chiasm
pituitary,enlargement
sella turcica,enlargement of

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