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Maternal Phenylketonuria:Magnetic Resonance Imaging of the Brain in Offspring J Pediatr 128:770-775, Levy,H.L.,et al, 1996 See this aricle in Pubmed Article Abstract Unlike PKU,white matter changes are not a feature of the brain effect in maternal PKU.However,hypoplasia of the corpus callosum is a feature of maternal PKU and is probably a result of inhibition of corpus callosum development at 8 to 20 weeks of gestation.The hypoplastic corpus callosum could be a marker for both brain effect in maternal PKU and may have implications for the cognitive deficits in these offspring.

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(click to filter results - removes previous filter) corpus callosum corpus callosum,hypoplastic mental retardation metabolic disorder,primary MRI MRI,abnormal phenylketonuria phenylketonuria,maternal

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