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Incidental aneurysms were detected in 40 individuals:38 of 438 individuals from 85 families without polycystic kidney disease or other diagnosed heritable disorders,and tow of 22 individuals from six families known to have polycystic kidney disease.The crude and age-adjusted prevalence of incidental intracranial aneurysms among screened first-degree relatives was 8.7(SE 1.3)%(95%CI 6.2-11.7)and 9.1(1.4)%(6.2-11.7),respectively,for the familial group and the crude prevalence for the polycystic kidney group was 9.1(6.1%)(1.1-29.2).Our results demonstrate a high prevalence of incidental intracranial aneurysms among first-degree relatives aged 30 years or older of patient with the condition indicate that risk of having an aneurysm is about four times higher for a close relative than for someone from the general population.Also,polycystic kidney disease families are a small fraction of the familial intracranial aneurysm families. |
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aneurysm aneurysm,asymptomatic aneurysm,berry aneurysm,intracranial aneurysm,intracranial,familial aneurysm,intracranial,screening for familial polycystic kidneys review article subarachnoid hemorrhage subarachnoid hemorrhage,familial
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