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Unruptured Intracranial Vertebral Artery Dissection, Clin Course & Serial Radiographic Imagings Stroke 28:370-374, Yoshimoto,Y.&Wakai,S., 1997 See this aricle in Pubmed Article Abstract Although recurrent ischemic attacks were observed in two patients,most (90%)subsequently made a good recovery and returned to their previous lifestyle.Five arteries showed the typical"string sign"or"pearl and string sign"on initial angiography.They changed in the follow-up examinations, which demonstrated either resolution of the stenosis or progression to complete occlusion.In contrast,the angiographic signs of complete occlusion(three arteries)or aneurysmal dilatation without luminal stenosis (four arteries)remained unchanged during the observation period of 5 months to 2.5 years.MRI was a sensitive tool for diagnosing intracranial vertebral artery dissection;intramural thrombus and intimal flab were the two major findings.MR angiography was also useful for demonstrating abnormalities of the arterial signal column such as pseudolumen or aneurysmal dilation.The natural history of unruptured intracranial vertebral artery dissection seems relatively benign,with a high probability(62%)of spontaneous angiographic cure.Some persistent aneurysmal dilation may be amenable to intravascular coil embolization.

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(click to filter results - removes previous filter) arterial dissection,vertebral MRI MRI,abnormal MRI,angiography MRI,serial prognosis

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