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Intermittent Cyclophosphamide & Prednisone Trtm of Polyneuropathy Assoc with Monocl Gamopathy of Undeter Sign
Neurol 47:1227-1233, Notermans,N.C.,et al, 1996
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Article Abstract
In an open prospective study,we analyzed the effect of cyclophosphamide (300 mg/m2 body surface daily for 4 days)combined with prednisone(40 mg/m2 body surface for 5 days)at 4 weeks intervals during 6 months in 16 patients with polyneuropathy associated with monoclonal gammopathy of undetermined significance(MGUS).In conclusion,short term treatment with intermittent cyclophosphamide and prednisone may have a long term favorable effect in patients with demyelinating polyneuropathy associated with MGUS.
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cyclophosphamide
immunosuppressive agents
monoclonal gammopathy
neuropathy
neuropathy,peripheral
neuropathy,peripheral,treatment
polyneuropathy
steroid
steroid therapy,CNS treatment and complications with
treatment of neurologic disorder
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