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The demographic characteristics and causes and severity of injury were similar in the hypothermia and normothermia groups.At 12 months,62%of the patients in the hypothermia group and 38%of these in the normothermia group had good outcomes(moderate,mild or no disabilities).The adjusted risk ratio for a bad outcome in the hypothermia group was 0.5(95% confidence interval,0.2 to 1.2).Hypothermia did not improve the outcomes in the patients with coma scores of 3 or 4 on admission.Among the patients with scores of 5 to 7,hypothermia was associated with significantly improved outcomes at 3 and 6 months(adjusted risk ratio for a bad outline, 0.2;95%confidence interval,0.2 to 1.0).Treatment with moderate hypothermia for 24 hours in patients with severe traumatic brain injury and coma scores of 5 to 7 on admission hastened neurologic recovery and may have improved the outcome. |
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