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Local Thrombolytic Therapy in Deep Cerebral Venous Thrombosis
Neurol 48:1613-1619, Smith,A.G.,et al, 1997
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Article Abstract
Thrombosis of the deep cerebral venous system is a rare entity with a very poor prognosis.We report two patients with thrombosis of the internal cerebral veins and vein of Galen who responded to local urokinase.We review all 49 cases of deep cerebral venous thrombosis in the English literature.The mortality rate for patients treated with either IV heparin or local thrombolytics was 13%compared with 48%in untreated patients(p=0. 037)).Based on this retrospective review of the literature and our two cases,we support the use of heparin or local thrombolytics in individual cases of deep cerebral venous thrombosis.
 
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cerebral venous thrombosis
cerebral venous thrombosis,deep
cerebrovascular accident,thrombolytic agents in treatment
fibrinolytic agents
fibrinolytic agents,intra-venous local infusion
heparin
internal cerebral vein
MRI
MRI,abnormal
MRI,venography
neuroradiology,interventional
review article
treatment of neurologic disorder
urokinase
vein of Galen

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