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Early epileptic seizures were diagnosed in 29 patients(2.4%).Seizures were significantly more frequent in patients with hemorrhagic stroke(4.3%)than in those with ischemic stroke(2%).Patients with seizures were significantly younger and significantly more likely to have acute confusional state,cortical involvement,large stroke and involvement of the parietal,frontal,occipital and temporal lobes than patients without seizures.The in-hospital mortality rate was 37.9%in the seizure group and 14.4%in the nonseizure group.After multivariate analysis,only cortical involvement(odds ratio of 6.01)and acute agitated confusional state(odds ratio of 4.44)were independent clinical factors for developing epileptic seizures.Cortical involvement in the neuroimaging studies and agitated acute confusional state at the onset of stroke were independent predictive factors of early seizures in first-ever stroke patients.The efficacy of anticonvulsant drugs in the prophylactic control of seizures should be assessed in prospective,randomized,double-blind clinical trials conducted in the subgroup of patients with the highest risk of developing epileptic seizures. |
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agitation cerebral infarction,hemorrhagic cerebrovascular accident cerebrovascular accident,agitated delirium following cerebrovascular accident,seizure with confusional state,acute mortality risk factors seizure
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