Click Here to return To Results

 

Frequent & Frequently Overlooked:Trtm-Induced Endocrine Dysf in Adult Long-Term Survivors of Primary Brain Tumors Neurol 49:498-506, Arlt,W.,et al, 1997 See this aricle in Pubmed Article Abstract Sixteen patients(52%)reported two or more symptoms suggestive of hypothyroidism;eight patients(26%)showed evidence of hypothalamic hypothyroidism.Patients had significantly lower serum baseline concentrations of cortisol and dehydroepiandrosterone sulfate than controls,but no manifest hypoadrenalism was noticed except in one patient with panhypopituitarism.Forty-seven percent of the male patients,but only six percent of the controls,suffered from erectile dysfunction;42%of the male patients(29%)presented with hyperprolactinemia and four women concurrently suffered from oligo-amenorrhea.In adult patients treated for primary brain tumors,endocrine dysfunction due to radiation-induced hypothalamic damage is common and has a significant impact on well being. Endocrinologic evaluation should be performed periodically in these patients.

Related Tags

(click to filter results - removes previous filter) chemotherapy,CNS treatment and complications with hypothalamus,damage to hypothyroidism neoplasm,primary intracerebral neoplasm,primary of CNS neoplasm,primary of CNS-treatment of neuroendocrinology prognosis quality of life radiation therapy,CNS treatment and complications with treatment of neurologic disorder

Click Here to return To Results