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Large subcortical infarctions may be due to cerebral embolism and cause cortical signs more frequently than small subcortical infarctions,which usually result from small vessel disease and are not associated with cortical findings.We evaluated 51 consecutive patients with a subcortical infarct on CT that was 1.5 cm or larger for a potential carotid or cardiac source of embolism and determined how frequently aphasia,hemineglect or gaze paresis occurred.A carotid or cardiac embolic source was identified in 63%of the total population with a carotid source occurring in 23%and a cardiac course occurring in 49%.More than one-half of the patients with hypertension or diabetes mellitus had an embolic source,whereas all patients without these risk factors had a possible carotid or cardiac source of embolism.Aphasia or hemineglect occurred in 39%of patients and gaze paresis occurred in 41%.Large subcortical strokes frequently result in a different clinical syndrome and from a different mechanism than small subcortical strokes. |
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aphasia basal ganglia,infarction CAT scan CAT scan,abnormal cerebral embolism cerebral embolism,cardiac origin cerebral embolism,carotid origin cerebral infarction cerebral infarction,subcortical cerebrovascular accident cerebrovascular accident,pathophysiology embolism,carotid artery gaze palsy middle cerebral artery,emboli to neglect striatocapsular infarction
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