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Cocaine-Induced Cerebral Vasoconstriction Detected in Humans with MR Angiography
JAMA 279:376-380, Kaufman,M.J.,et al, 1998
See this aricle in Pubmed
Article Abstract
cocaine administration induced dose-related cerebral vasoconstriction on magnetic resonance angiograms.These changes occurred at low cocaine doses and in the absence of other risk factors,including polydrug abuse, hypertension,or cerebrovascular disease.Outcome stratification by prior cocaine use statistically strengthened the relationship between cocaine administration and vasoconstriction suggesting that cocaine may have cumulative residual effect in promoting cerebrovascular dysfunction.
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cerebrovascular disease
cocaine
drug abuse
MRI
MRI,abnormal
MRI,angiography
vasospasm,cerebral
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