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Anesthetic and Surgical Complictions in 219 Cases of Myotonic Dystrophy
Neurol 49:1646-1650, Mathieu,J.,et al, 1997
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Article Abstract
The objective of this study was to assess the frequency,type,and severity of perioperative complications after a first surgery under general anesthesia in patients with myotonic dystrophy(DM)and to measure the association with suspected risk factors.Numerous cases of perioperative complications in DM patients have been reported.Hazards have been associated with the use of thiopentone,suxamethonium,neostigmine,and halothane.A retrospective study of perioperative complications was conducted for 219 DM patients who had their first surgery under general anesthesia at the Chicoutimi Hospital.The overall frequency of complications was 8.2%(18 of 219).Most complications(16 of 18)were pulmonary,including five patients with acute ventilatory failure necessitating ventilatory support,four patients with atelectasis,and three patients with pneumonia.Using multivariate analysis,we found that the risk of perioperative pulmonary,and three patients with pneumonia.Using multivariate analysis,we found that the risk of perioperative pulmonary complications(PPC)was significantly higher after an upper abdominal surgery(odds ratio(OR),24.4%;95%CI,1.5 to 134.4).The likelihood of PPC was not related to any specific anesthetic drug.Because of the increased risk of PPC,careful monitoring during the early postoperative period,protection of upper airways,chest physiotherapy,and incentive spirometry are mandatory in all symptomatic DM patients,particularly those with a severe muscular disability or those who have undergone an upper abdominal surgery.
 
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anesthesia,general
atelectasis
myotonia dystrophica
neurologic complications of,surgery
pneumonia
respiratory failure
risk factors

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