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Stereotactic pallidotomy for Trtm of Parkinson's Disease, Efficacy & Adverse Effects at 6 Mo in 26 Pts
Neurol 50:434-438, Shannon,K.M.,et al, 1998
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Article Abstract
Serious adverse effects occurred in eight patients and included one fatal deep and three nonfatal frontal lobe hemorrhages with resultant language or behavioral deficits.Nonhemorrhagic complications included one hemiparesis and three frontal lobe syndromes.Pallidotomy improves PD motor disability in the"off"state.Peak dose dyskinesias are reduced,although other aspects of"on"motor function are unchanged.Although morbidity may limit its use,pallidotomy is effective in targeting particular symptoms such as unremitting dyskinesia and severe"off"motor disability in advanced PD.
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dyskinesia
frontal lobe,behavior with disease of
iatrogenic neurologic disorders
intracerebral hemorrhage
mortality
neurologic complications of,surgery
pallidotomy
Parkinson disease
Parkinson disease,fluctuations in
Parkinson disease,on-off phenomena in
Parkinson disease,surgical treatment of
Parkinson disease,treatment of
prognosis
stereotaxic surgery
treatment of neurologic disorder
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