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Of 453 consecutive patients with a presumed diagnosis of acute stroke referred to our department between March 1996 and August 1997,100 patients (22%)were treated with intravenous thrombolysis,26%of them within 90 minutes of symptom onset.The average time of stroke onset to the arrival to our department was 78 minutes,and from arrival to treatment 48 minutes. After 3 months,53 patients recovered to fully independent function.The rates of total,symptomatic,and fatal intravertebral hemorrhage were 11%, 5%,and 1%respectively.Overall mortality was 12%.Thrombolysis with rtPA was effectively applied in routine management of stroke patients in a community-based approach with acceptable efforts and without additional costs.Under these circumstances,outcome and complication rates were comparable to those of multicenter trials. |
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